---
product_id: 673590358
title: "PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being"
brand: "pranapets"
price: "€ 71.97"
currency: EUR
in_stock: true
reviews_count: 8
category: "Prana Pets"
url: https://www.desertcart.nl/products/673590358-pranapets-lignans-and-melatonin-with-biotin-blend-naturally-aids-in
store_origin: NL
region: Netherlands
---

# Melatonin for symptom relief Precise Lignans dosing Biotin for skin & coat health PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being

**Brand:** pranapets
**Price:** € 71.97
**Availability:** ✅ In Stock

## Summary

> 🌟 Restore your dog’s spark with nature’s precision blend!

## Quick Answers

- **What is this?** PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being by pranapets
- **How much does it cost?** € 71.97 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.nl](https://www.desertcart.nl/products/673590358-pranapets-lignans-and-melatonin-with-biotin-blend-naturally-aids-in)

## Best For

- pranapets enthusiasts

## Why This Product

- Trusted pranapets brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Trusted by Pet Parents:** Highly rated with real success stories—join thousands who’ve seen their dogs thrive again.
- • **Clean & Conscious Formula:** No artificial flavors, sorbitol, or sucrose. Non-GMO, gluten & soy free for peace of mind.
- • **Optimized Cortisol Control:** Formulated to support healthy cortisol levels, helping your dog regain vitality naturally.
- • **Targeted Cushing’s Relief:** Melatonin & lignans team up to ease excessive thirst, panting & urination—because your dog deserves balance.
- • **Enhanced Skin & Coat Wellness:** Added biotin promotes a shiny coat, strong nails, and reduces hot spots—visible health you can see.

## Overview

PranaPets Lignans & Melatonin with Biotin Blend is a scientifically adjusted supplement designed for dogs over 25 lbs to naturally alleviate symptoms of Cushing’s disease. Combining precise doses of lignans and melatonin, it supports healthy cortisol levels while biotin enhances skin, coat, and nail health. Free from artificial additives and allergens, this clean formula is trusted by pet owners seeking effective, holistic adrenal support.

## Description

desertcart.com : PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being : Pet Supplies

Review: It worked for us and our 13 year old dog. - As far as I’m concerned this stuff really works if your dog has Cushing disease. Our dog started the adrenal gland balance drops and then we included the lignans and melatonin support. She did an about face and is back to her normal self. In fact she’s acting like a puppy again at 13 years old. For all the naysayers out there, maybe it doesn’t work for your dog and I’m sorry but for new people who are considering it, what’s it hurt to try, especially if your dog is getting old and you’re at your wits end. That’s where we were and we tried it and it works great. Good luck to you if you’re going to give it a try. I really hope it works for you and your dog!
Review: Really helped calm my doggy and let her get rest - My little doggie was diagnosed with Cushing disease. In the evenings especially she was miserable. This medicine helped to calm her and let her rest. I still ended up putting her on vet prescribed medicine, but this really helped us get thru that period before testing to get her on meds. I was hoping it and the other homeopathic meds we tried would work, but after a couple of months it didn’t seem to be enough. I will still use and recommend this product as it really did help settle her down. On nights when she needs a little extra help, I still give her some.

## Features

- 𝐂𝐔𝐒𝐇𝐈𝐍𝐆’𝐒 𝐒𝐔𝐏𝐏𝐎𝐑𝐓 – Melatonin and lignans together help manage the symptoms of Cushing’s, such as excessive thirst, panting and urination. Get even better results when used with Prana Pets Adrenal Balance.
- HEALTHY CORTISOL LEVELS - Adjusted for more effective support in lowering cortisol levels, especially helpful for dogs with Cushing’s.
- NEW FORMULA - Improved Lignans and Melatonin Blend formula offers more precise dosing with new added benefits. Now with adjusted amounts of SDG lignans and melatonin for more accurate dosing.
- ADDED BIOTIN - Now includes biotin for healthier skin, coat and nails. Promotes a shiny coat, healthy skin and strong nails while helping to reduce hot spots and hair loss.
- LESS JUNK - No more artificial flavors, sorbitol and sucrose so you can worry less about what you are giving your beloved pooch. Non-GMO, Gluten & Soy Free.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0DFJCL5BG |
| ASIN  | B0DFJCL5BG |
| Age Range Description | All Life Stages |
| Best Sellers Rank | #8,029 in Pet Supplies ( See Top 100 in Pet Supplies ) #42 in Dog Herbal Supplements |
| Brand Name | PranaPets |
| Color | Beige |
| Customer Reviews | 4.3 4.3 out of 5 stars (520) |
| Date First Available | August 22, 2024 |
| Date First Available  | August 22, 2024 |
| Directions | Dogs 26-40 Lb: 2-3 Tablets Per Day. Recommend 1 tablet in the morning & 1-2 tablets at bedtime |
| Included Components | Tablets |
| Item Package Dimensions L x W x H | 3.78 x 1.93 x 1.89 inches |
| Item Weight | 0.09 Kilograms |
| Item model number | PPMELLIG2-BIO |
| Item model number  | PPMELLIG2-BIO |
| Manufacturer | PranaPets |
| Manufacturer  | PranaPets |
| Model Name | L&M w/ Biotin |
| Package Dimensions  | 3.78 x 1.93 x 1.89 inches; 3.21 ounces |
| Size | Over 25 lb (w/ Biotin) |
| Specific Uses for Product | Active |
| Target Audience Keyword | dogs |
| Warranty Description | 366 |

## Product Details

- **Brand:** PranaPets
- **Flavor:** Beef
- **Item Weight:** 0.09 Kilograms
- **Product Benefits:** Anti-Hairfall, Cushing's relief for dogs, Immune Support, Skin Care

## Images

![PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being - Image 1](https://m.media-amazon.com/images/I/61r5wEqvgLL.jpg)
![PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being - Image 2](https://m.media-amazon.com/images/I/61beYML0zDL.jpg)
![PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being - Image 3](https://m.media-amazon.com/images/I/611zPlTqhYL.jpg)
![PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being - Image 4](https://m.media-amazon.com/images/I/61T+VAV3mSL.jpg)
![PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being - Image 5](https://m.media-amazon.com/images/I/61nM8KYVoIL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: What is new and improved about this formula?**
A: Our improved Lignans and Melatonin Blend formula offers more precise dosing with new added benefits. Now with adjusted amounts of SDG lignans and melatonin for more accurate dosing, plus biotin for a healthier skin, coat, and nails.

**Q: Can I use Lignans and Melatonin with other Prana Pets supplements?**
A: Absolutely! We recommend combining our supplements for a full daily health regimen. Our proprietary blends were formulated to work together synergistically to keep your pet looking and feeling their best.

**Q: What other supplements should I give my Cushing's dog?**
A: We recommended Adrenal Balance, Lignans and Melatonin, Immunity Blend and Liver Supplement for full Cushing's support.

**Q: Should this product only be used for Cushing's dogs?**
A: No! Lignans and Melatonin is great for any nervous or high-strung dog who suffers from things like separation anxiety or other phobias. It's great to calm nerves for trips to the vet or during loud 4th of July fireworks, too.

## Customer Reviews

### ⭐⭐⭐⭐⭐ It worked for us and our 13 year old dog.
*by D***L on January 22, 2026*

As far as I’m concerned this stuff really works if your dog has Cushing disease. Our dog started the adrenal gland balance drops and then we included the lignans and melatonin support. She did an about face and is back to her normal self. In fact she’s acting like a puppy again at 13 years old. For all the naysayers out there, maybe it doesn’t work for your dog and I’m sorry but for new people who are considering it, what’s it hurt to try, especially if your dog is getting old and you’re at your wits end. That’s where we were and we tried it and it works great. Good luck to you if you’re going to give it a try. I really hope it works for you and your dog!

### ⭐⭐⭐⭐⭐ Really helped calm my doggy and let her get rest
*by B***H on February 28, 2026*

My little doggie was diagnosed with Cushing disease. In the evenings especially she was miserable. This medicine helped to calm her and let her rest. I still ended up putting her on vet prescribed medicine, but this really helped us get thru that period before testing to get her on meds. I was hoping it and the other homeopathic meds we tried would work, but after a couple of months it didn’t seem to be enough. I will still use and recommend this product as it really did help settle her down. On nights when she needs a little extra help, I still give her some.

### ⭐⭐⭐⭐ Keeping my HOPES 🥰🙏🏼🤞🏼up! 🐶
*by S***S on September 10, 2025*

MY personal experience thus far: 🙏🏼 Just started … I have a rescue 🐶 doggy, positivity confident that suffers from Cushing disease / syndrome with major! skin issues / infections, joint pain inflammation and unhappiness and over discomfort about every 3-4 months relapses, sometimes loosing some of his beautiful hair coat🐶, triggered by allergies. The PranaPets Lignans and Metlaronin Blend with Biotin,’ has been recommended by our veterinarian as an alternative holistic treatment according to her advice for us. We Cannot afford to spend the $4,000-$5,000 on 'Cushing’ related -tests related, which STILL could NOT be a 💯 % reliable diagnosis for my dog according to our vet. ☝🏼In the Meantime —our Vet recommended a HEALTHY nutrious restricted food diet, rich in omega oils 3, 5, 7, 9 and special dermatological shampoos conditioner etc (which I found on on Amazon much cheaper). The PRANAPETS is part of our regimen. Our Vet specifically recommended this holistic The blend of ingredients in PRANA🐶PETS, Lignans and Melatonin blend with Biotin that I noticed are FREE of any harmful inactive ingredients according to my purchase. I was buying the INDIVIDUAL ingredient of each in this product, which is MUCH more expensive and not knowing if each dose à was exact or consistent. THIS PRODUCT is Great 👍 !! It is ALL in one!! AND, the BLEND of Active Ingredients is EXACTLY what the Vet recommends or prescribes for ‘something-liké potentially Cushings disease 🦠 and the health & benefits of MY dogs symptoms including his endocrine systems, adrenals and cortisol and thyroid hormones and brain…. we are trying an alternative healthcare approach for now. Amazon has some very good options for probiotics and immune-calm that are helping to provide overall daily maintenance balance AND as I am discovering at a lower cost. ‼️PLEASE 🐶NOTE: I did N🚫t get paid, endorsed, etc or was asked for this review. Thank you . Best !

## Frequently Bought Together

- PranaPets Lignans & Melatonin with Biotin Blend Naturally Aids in Relieving Symptoms of Cushing’s in Dogs Over 25 lb | Promote Healthy Balance & Overall Well-Being
- PranaPets Adrenal Balance for Dogs with Cushing’s | Naturally Relieves Symptoms of Cushing's in Dogs | Herbal Formula for Dogs with Cushing’s
- PranaPets Immunity Blend Supplement for Dogs & Cats | Naturally Helps Relieve Fatigue & Weakness in Pets | Promoting Increased Energy, Normal Appetite & Immune Support

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*Product available on Desertcart Netherlands*
*Store origin: NL*
*Last updated: 2026-03-09*