---
product_id: 63185961
title: "Penetrex Joint & Muscle Therapy Duo - Soothing Relief for Back, Neck, Hands, Feet & Nerves - Rub with Arnica, Vitamin B6 MSM & Boswellia - 2oz, 4oz"
brand: "penetrex"
price: "€ 74.06"
currency: EUR
in_stock: true
reviews_count: 9
category: "Penetrex"
url: https://www.desertcart.nl/products/63185961-penetrex-joint-and-muscle-therapy-duo-soothing-relief-for-back
store_origin: NL
region: Netherlands
---

# Fast-absorbing, non-greasy formula Non-NSAID, natural pain relief blend Clinically-studied botanicals for muscle & joint support Penetrex Joint & Muscle Therapy Duo - Soothing Relief for Back, Neck, Hands, Feet & Nerves - Rub with Arnica, Vitamin B6 MSM & Boswellia - 2oz, 4oz

**Brand:** penetrex
**Price:** € 74.06
**Availability:** ✅ In Stock

## Summary

> 🌟 Unlock your body's potential with pain-free power!

## Quick Answers

- **What is this?** Penetrex Joint & Muscle Therapy Duo - Soothing Relief for Back, Neck, Hands, Feet & Nerves - Rub with Arnica, Vitamin B6 MSM & Boswellia - 2oz, 4oz by penetrex
- **How much does it cost?** € 74.06 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.nl](https://www.desertcart.nl/products/63185961-penetrex-joint-and-muscle-therapy-duo-soothing-relief-for-back)

## Best For

- penetrex enthusiasts

## Why This Product

- Trusted penetrex brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Safe for Daily Hustle:** Gentle, non-NSAID formula perfect for long-term muscle & joint care
- • **Invisible Comfort, Anytime Use:** Fragrance-free, no greasy residue—wear it at work or before bed
- • **Trusted by Millions, Made in USA:** Over 2 million users rely on Penetrex’s quality and effectiveness
- • **Targeted Relief for Everyday Warriors:** Soothes back, neck, knees & hands without harsh chemicals
- • **Powerhouse Ingredients, Proven Results:** Arnica, MSM, Vitamin B6 & Boswellia team up for enhanced recovery

## Overview

Penetrex Joint & Muscle Therapy Duo is a fast-absorbing, non-NSAID cream formulated with Arnica, MSM, Vitamin B6, and Boswellia to provide targeted relief for back, neck, knees, hands, and nerves. Designed for active professionals and athletes, it offers natural, fragrance-free support without greasy residue, making it ideal for daily use. Trusted by over 2 million users and made in the USA, Penetrex helps reduce discomfort from exercise, repetitive strain, and chronic tension safely and effectively.

## Description

Buy Penetrex Joint & Muscle Therapy Duo - Soothing Relief for Back, Neck, Hands, Feet & Nerves - Rub with Arnica, Vitamin B6 MSM & Boswellia - 2oz, 4oz on desertcart.com ✓ FREE SHIPPING on qualified orders

Review: Works SO MUCH BETTER than Icy Hot! - I honestly can't believe how well this works! I did a workout where I was sore for 5 straight days. The next week, I did the SAME workout, put on this cream before bed, and woke up...not sore. I didn't trust it, because it seemed like magic, but after going through a whole bottle of this stuff, I'm blown away! SECRET TIP: If you put it on the night you worked out, before bed, and don't wait until you're ALREADY sore? I find it works even better. Maybe 50% better, in that case? It's still helpful on already sore muscles, but not as dramatic. Why I like this: -I have tried Sore No More, Icy Hot, and at least 3 kinds of "hippie balms" with natural ingredients and all that, and most of them burned, felt cold, and then...did nothing. THIS ONE actually moves the needle! -It doesn't burn. So you don't have to worry about accidentally getting it anywhere, um, sensitive. -It doesn't make you smell like a tube of toothpaste. (No noticeable odor at all). -It's thinner, when you get the roll on applicator, so it's not as thick and sticky to put on. You still need to wait for it to dry for a second before putting fabric on top, but it's way, way faster than the creams and ointments and doesn't get all over everything. -My husband finds this much more effective for putting on hairy legs, whereas creams and ointments just get all gummed up in the hair and it's gross. I LOVE this stuff and I've already gone through a whole tube. Buying a spare for my big horseback riding trip so I can share with friends!
Review: Penetrex works by keeping your pain at bay so YOU can find and fix the underlying problems - Let's get something straight from the get-go; Penetrex is a pain reliever (even said so on the label) and as a pain reliever, it works surprisingly well. However, many customer placed too much faith in the creme as a "cure-all" for their disorders/diseases/pain (basing on the 3 stars reviews and lower). In my perspective, Penetrex works by keeping your pain at bay so YOU can find and fix the underlying problems. And there lies the problem. There is a major emphasis on the YOU part. Now to paint my scenario. I was diagnosed with Patellofemoral Syndrome by two different clinics. The pain became so unbearable that I was limited to upper body exercises for three whole months. Usually in these cases, icing and rest would be prescribed, and since X-rays and MRI both showed no signs of abnormalities, ice and rest seemed like the only logical solution. I too was under the impression that my knee would recover in time but as the clock ticked, long car rides and extensive sittings became more and more unbearable. After 3 months of doing nothing, I took it upon myself to find a solution and after extensive reading and tinkering and soul searching, it seems my vastus medialis (inner quadriceps muscle) was at fault. This "little fault" caused a myriad of messes: My lateralis tightened up, I always felt a tug in my right hip flexor, and because of the tug, my t-spine (I'm a nerd, I know) would prematurely round when I squat. EMG results confirmed my hypothesis; my VMO would shut down as soon as I ventured beyond parallel during any sort of exercises. Now that I am armed with this discovery, I was ready to make drastic changes. The only drawback was the massive, excruciating pain that accompanied rehab and therapy work, even the lightest workload, such as bodyweight squat and peterson step-up. That's when I discovered Penetrex. The creme allowed me to progressively strengthen my VMO, without having to endure the torment. Here is another scenario: My friend who is currently suffering from a similar knee issue. His VMO rides even higher than mine, almost 4 inches above the kneecap. He is a long distance runner and I am a powerlifter. Two people from two different sports, suffering from the same problem. After convincing him to drop running for a while (athletes can be very hard-headed) and go through an extensive rehab program, his kneecap no longer slides and I bet with a little more time, the pain will disappear altogether. Yes, I do wholeheartedly recommend Penetrex for all acute injuries (and some chronic). I came to realize that there are a certain few customers who view Penetrex as nothing more than a glorified DMSO product, and to a certain extent, I agree with them. However, that is not necessarily a bad thing! Pure DMSO is extremely potent and works well to ease tendinitis and other symptoms. I myself have used DMSO but found that with multiple applications in a day, even with less potent concentration and/or mixes, it tends to eat away the skin fairly fast. Penetrex does not do this and eventually you have to ramp up the dosage (while doing rehab work, of course) to speed up the healing process. Whether it is straight DMSO or Penetrex, like I said, YOU will have to play a huge part in the recovery stage. Do not expect to dabble on the creme and by some miracle, your tendinitis will dissipate. If you play golf and suffer from elbow and back pain, common sense would dictate that you take some time off and REALLY find that kink in your kinetic chain. Common sense also tells us that golfing is a very one-sided sport, so wouldn't it make sense to focus on a bit of weight training to strength the oblique/back muscles and biceps/triceps? If you're a long distance runner and are suffering from knee pain, don't continue grinding your knees to dust! Stop running and find the underlying problem! Take up weightlifting to strengthen the entire posterior chain; more muscle = less force absorption on the knees when the feet hit the ground. And judging from the numerous runners who are diagnosed with some kind of patella problem, the VMO is at fault. This review should not be viewed as me chastising or as a lecture but as me sharing one of my humble life experiences :) We all have to do things that we hate and being a strength athlete who absolutely loved to squat, it was heartbreaking and a blow to my ego when I was reduced to doing peterson step-ups and body weight lunges. If you truly love what you do, be it golfing, running, lifting, or playing competitive sports, then do everything in your power to make sure you can continuing doing what you're doing!

## Features

- Trusted Daily Relief for Back, Neck, Knee, Shoulder & Hand Discomfort – Non-NSAID Formula. Penetrex provides targeted support for common problem areas including lower back, stiff neck, achy knees, shoulder tension, and hand soreness. Formulated without NSAIDs (non-steroidal anti-inflammatory drugs) for those seeking natural alternatives to oral medications or medicated patches for routine joint and muscle strain.
- Professional-Grade Ingredients: Arnica, MSM, Vitamin B6 & Boswellia for Enhanced Support. Enhanced with clinically-studied botanicals and nutrients recognized for their soothing properties. Arnica montana has been used traditionally for centuries, while MSM (Methylsulfonylmethane), Vitamin B6, and Boswellia Serrata work synergistically to support muscles and joints experiencing occasional discomfort from exercise, repetitive motion, or daily activity.
- Fast-Absorbing, Non-Greasy Cream – No Menthol Smell, Won't Stain Clothing. Lightweight, fast-penetrating formula absorbs quickly into skin without leaving oily residue, sticky feeling, or transferring to clothes or bed sheets. Unlike menthol-based products with strong medicinal odors, Penetrex is fragrance-free with no overpowering scent, making it ideal for use anytime – at work, before bed, or during your daily routine.
- Ideal for Active Adults, Athletes & Those Managing Chronic Tension – Safe for Long-Term Use. Perfect for fitness enthusiasts dealing with post-workout soreness, office workers with repetitive strain, aging adults experiencing stiffness, or anyone managing ongoing discomfort in joints and muscles. Gentle enough for consistent daily application without the concerns associated with prolonged NSAID use.
- Trusted by Over 2 Million Users and Made in USA with Quality Standards You Can Count On. With a loyal customer base spanning over a decade, Penetrex has become a household name for natural topical support. Manufactured in the USA following strict quality standards, and suitable for those seeking vegan-friendly, paraben-free formulations.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07BMKC87P |
| ASIN  | B07BMKC87P |
| Active Ingredients | chloride |
| Additional Features | Targeted |
| Age Range Description | Kid |
| Best Sellers Rank | #919 in Health & Household ( See Top 100 in Health & Household ) #1 in Joint & Muscle Pain Relief Rubs |
| Brand Name | Penetrex |
| Container Type | Jar |
| Customer Reviews | 4.2 4.2 out of 5 stars (97,735) |
| Date First Available  | June 11, 2019 |
| Diet Type | Vegan |
| Flavor | Unflavored |
| Is Discontinued By Manufacturer  | No |
| Item Form | Cream |
| Item Weight | 0.38 Pounds |
| Manufacturer | Biomax Health Products, Inc. |
| Manufacturer  | Biomax Health Products, Inc. |
| Package Dimensions  | 6.3 x 4.45 x 3.7 inches; 6.08 ounces |
| Package Type Name | Tube |
| Product Benefits | Muscle Therapy |
| Specific Uses For Product | Joint and Muscle Therapy |
| Target Use Body Part | Back |
| UPC | 867299000063 |
| Unit Count | 6 Fluid Ounces |

## Product Details

- **Active Ingredients:** chloride
- **Brand:** Penetrex
- **Item Weight:** 0.38 Pounds
- **Product Benefits:** Muscle Therapy
- **Specific Uses For Product:** Joint and Muscle Therapy

## Images

![Penetrex Joint & Muscle Therapy Duo - Soothing Relief for Back, Neck, Hands, Feet & Nerves - Rub with Arnica, Vitamin B6 MSM & Boswellia - 2oz, 4oz - Image 1](https://m.media-amazon.com/images/I/512y-O8P3CL.jpg)
![Penetrex Joint & Muscle Therapy Duo - Soothing Relief for Back, Neck, Hands, Feet & Nerves - Rub with Arnica, Vitamin B6 MSM & Boswellia - 2oz, 4oz - Image 2](https://m.media-amazon.com/images/I/61D467GJZPL.jpg)
![Penetrex Joint & Muscle Therapy Duo - Soothing Relief for Back, Neck, Hands, Feet & Nerves - Rub with Arnica, Vitamin B6 MSM & Boswellia - 2oz, 4oz - Image 3](https://m.media-amazon.com/images/I/71sw+lAr3JL.jpg)
![Penetrex Joint & Muscle Therapy Duo - Soothing Relief for Back, Neck, Hands, Feet & Nerves - Rub with Arnica, Vitamin B6 MSM & Boswellia - 2oz, 4oz - Image 4](https://m.media-amazon.com/images/I/71uobSr6RLL.jpg)
![Penetrex Joint & Muscle Therapy Duo - Soothing Relief for Back, Neck, Hands, Feet & Nerves - Rub with Arnica, Vitamin B6 MSM & Boswellia - 2oz, 4oz - Image 5](https://m.media-amazon.com/images/I/71Qlf31cxRL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: Does product contain magnesium which is a muscle relaxer?**
A: Go to Amazon find penetrex product.  Click on picture that shows the back of the Jar.  Zoom and read a list of contents.

**Q: is it possible this product will work on the upper thigh muscle**
A: As a senior with two hip replacements, I get horrific charley horses and cramping in upper thights, inner thighs and hamstrings from sitting or standing too long. Flying is especially painful because you can't move around. Penetrex is the only product that helps prevent the cramping and charley horses. I apply to thighs before flying or going to fairs, concerts, sports or activities that include alot of sitting or walking. Also, great after gardening. Nothing else has worked as well as Penetrex and I have a medicine cabinet of products that haven't worked.

**Q: Do you have 2oz size ?**
A: I bought the 2 oz size on Amazon first to try it. I'm going to buy the 4 oz + 2 oz bundle. This stuff is the only thing that I've tried that helps my arthritis.

**Q: What’s the difference between the old version and this new version?**
A: Don't know. I've been ordering Penetrex for over two years now and didn't notice difference.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Works SO MUCH BETTER than Icy Hot!
*by M***H on February 13, 2026*

I honestly can't believe how well this works! I did a workout where I was sore for 5 straight days. The next week, I did the SAME workout, put on this cream before bed, and woke up...not sore. I didn't trust it, because it seemed like magic, but after going through a whole bottle of this stuff, I'm blown away! SECRET TIP: If you put it on the night you worked out, before bed, and don't wait until you're ALREADY sore? I find it works even better. Maybe 50% better, in that case? It's still helpful on already sore muscles, but not as dramatic. Why I like this: -I have tried Sore No More, Icy Hot, and at least 3 kinds of "hippie balms" with natural ingredients and all that, and most of them burned, felt cold, and then...did nothing. THIS ONE actually moves the needle! -It doesn't burn. So you don't have to worry about accidentally getting it anywhere, um, sensitive. -It doesn't make you smell like a tube of toothpaste. (No noticeable odor at all). -It's thinner, when you get the roll on applicator, so it's not as thick and sticky to put on. You still need to wait for it to dry for a second before putting fabric on top, but it's way, way faster than the creams and ointments and doesn't get all over everything. -My husband finds this much more effective for putting on hairy legs, whereas creams and ointments just get all gummed up in the hair and it's gross. I LOVE this stuff and I've already gone through a whole tube. Buying a spare for my big horseback riding trip so I can share with friends!

### ⭐⭐⭐⭐⭐ Penetrex works by keeping your pain at bay so YOU can find and fix the underlying problems
*by D***G on May 3, 2012*

Let's get something straight from the get-go; Penetrex is a pain reliever (even said so on the label) and as a pain reliever, it works surprisingly well. However, many customer placed too much faith in the creme as a "cure-all" for their disorders/diseases/pain (basing on the 3 stars reviews and lower). In my perspective, Penetrex works by keeping your pain at bay so YOU can find and fix the underlying problems. And there lies the problem. There is a major emphasis on the YOU part. Now to paint my scenario. I was diagnosed with Patellofemoral Syndrome by two different clinics. The pain became so unbearable that I was limited to upper body exercises for three whole months. Usually in these cases, icing and rest would be prescribed, and since X-rays and MRI both showed no signs of abnormalities, ice and rest seemed like the only logical solution. I too was under the impression that my knee would recover in time but as the clock ticked, long car rides and extensive sittings became more and more unbearable. After 3 months of doing nothing, I took it upon myself to find a solution and after extensive reading and tinkering and soul searching, it seems my vastus medialis (inner quadriceps muscle) was at fault. This "little fault" caused a myriad of messes: My lateralis tightened up, I always felt a tug in my right hip flexor, and because of the tug, my t-spine (I'm a nerd, I know) would prematurely round when I squat. EMG results confirmed my hypothesis; my VMO would shut down as soon as I ventured beyond parallel during any sort of exercises. Now that I am armed with this discovery, I was ready to make drastic changes. The only drawback was the massive, excruciating pain that accompanied rehab and therapy work, even the lightest workload, such as bodyweight squat and peterson step-up. That's when I discovered Penetrex. The creme allowed me to progressively strengthen my VMO, without having to endure the torment. Here is another scenario: My friend who is currently suffering from a similar knee issue. His VMO rides even higher than mine, almost 4 inches above the kneecap. He is a long distance runner and I am a powerlifter. Two people from two different sports, suffering from the same problem. After convincing him to drop running for a while (athletes can be very hard-headed) and go through an extensive rehab program, his kneecap no longer slides and I bet with a little more time, the pain will disappear altogether. Yes, I do wholeheartedly recommend Penetrex for all acute injuries (and some chronic). I came to realize that there are a certain few customers who view Penetrex as nothing more than a glorified DMSO product, and to a certain extent, I agree with them. However, that is not necessarily a bad thing! Pure DMSO is extremely potent and works well to ease tendinitis and other symptoms. I myself have used DMSO but found that with multiple applications in a day, even with less potent concentration and/or mixes, it tends to eat away the skin fairly fast. Penetrex does not do this and eventually you have to ramp up the dosage (while doing rehab work, of course) to speed up the healing process. Whether it is straight DMSO or Penetrex, like I said, YOU will have to play a huge part in the recovery stage. Do not expect to dabble on the creme and by some miracle, your tendinitis will dissipate. If you play golf and suffer from elbow and back pain, common sense would dictate that you take some time off and REALLY find that kink in your kinetic chain. Common sense also tells us that golfing is a very one-sided sport, so wouldn't it make sense to focus on a bit of weight training to strength the oblique/back muscles and biceps/triceps? If you're a long distance runner and are suffering from knee pain, don't continue grinding your knees to dust! Stop running and find the underlying problem! Take up weightlifting to strengthen the entire posterior chain; more muscle = less force absorption on the knees when the feet hit the ground. And judging from the numerous runners who are diagnosed with some kind of patella problem, the VMO is at fault. This review should not be viewed as me chastising or as a lecture but as me sharing one of my humble life experiences :) We all have to do things that we hate and being a strength athlete who absolutely loved to squat, it was heartbreaking and a blow to my ego when I was reduced to doing peterson step-ups and body weight lunges. If you truly love what you do, be it golfing, running, lifting, or playing competitive sports, then do everything in your power to make sure you can continuing doing what you're doing!

### ⭐⭐⭐⭐ Mechanism of Operation
*by K***S on May 20, 2011*

I've been using this now for 2 weeks, and am downgrading my rating from 5 to 4. I think it may be working somewhat, but after 2 weeks, I'm definitely not dramatically better. I do like having something to rub on there that seems vaguely soothing and may be helpful, but I was hoping for more. Also, from the product description online, I thought DMSO was the top ingredient. Looking at DMSO products, many people reported pain relief. And it's well known that DMSO is effective transdermally, and carries other ingredients through the skin. But it's also reported to smell fishy. So I figured Penetrex had solved that problem. Penetrex does smell fine, but DMSO is pretty far down the list of ingredients on the jar itself. The top ingredient is water, and the next one is Arnica. My original review: I've got acute tennis elbow. In searching for how this product could produce the results many are reporting (and a few denying) I came across a helpful passage on this page:[oops, I guess I can't put the link. I'll edit to say I just Googled DMSO, and read the top result.] I'll update later with my results. I'm giving it a 5 star rating in anticipation, but will change it if warranted. "DMSO Penetrates Membranes and Eases Pain The first quality that struck Dr. Jacob about the drug was its ability to pass through membranes, an ability that has been verified by numerous subsequent researchers.1 DMSO's ability to do this varies proportionally with its strength--up to a 90 percent solution. From 70 percent to 90 percent has been found to be the most effective strength across the skin, and, oddly, performance drops with concentrations higher than 90 percent. Lower concentrations are sufficient to cross other membranes. Thus, 15 percent DMSO will easily penetrate the bladder.2 In addition, DMSO can carry other drugs with it across membranes. It is more successful ferrying some drugs, such as morphine sulfate, penicillin, steroids, and cortisone, than others, such as insulin. What it will carry depends on the molecular weight, shape, and electrochemistry of the molecules. This property would enable DMSO to act as a new drug delivery system that would lower the risk of infection occurring whenever skin is penetrated. DMSO perhaps has been used most widely as a topical analgesic, in a 70 percent DMSO, 30 percent water solution. Laboratory studies suggest that DMSO cuts pain by blocking peripheral nerve C fibers.3 Several clinical trials have demonstrated its effectiveness,4,5 although in one trial, no benefit was found.6 Burns, cuts, and sprains have been treated with DMSO. Relief is reported to be almost immediate, lasting up to 6 hours. A number of sports teams and Olympic athletes have used DMSO, although some have since moved on to other treatment modalities. When administration ceases, so do the effects of the drug. Dr. Jacob said at a hearing of the U.S. Senate Subcommittee on Health in 1980, "DMSO is one of the few agents in which effectiveness can be demonstrated before the eyes of the observers....If we have patients appear before the Committee with edematous sprained ankles, the application of DMSO would be followed by objective diminution of swelling within an hour. No other therapeutic modality will do this." Chronic pain patients often have to apply the substance for 6 weeks before a change occurs, but many report relief to a degree they had not been able to obtain from any other source."

## Frequently Bought Together

- Penetrex (Value Bundle) Pain Relief Therapy:: Home&Travel Solution Contains One Large(4 Oz.)&One Travel-Ready(Tsa Approved 2 Oz. Size)For On-The-Go Relief
- Gold Bond Body Lotion - Extra Strength 14 oz Cream

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*Product available on Desertcart Netherlands*
*Store origin: NL*
*Last updated: 2026-03-12*