

🧠 Unlock your brain’s full potential—stay sharp, stay ahead.
Nootropics Depot 4'-DMA-7,8-DHF Capsules provide a potent 10mg dose of a powerful flavone derivative known for enhancing sustained mental focus and neurogenesis. With effects lasting up to 15 hours, this supplement supports clean, jitter-free cognitive activation ideal for professionals seeking enhanced productivity and brain health. Its compatibility with popular nootropic stacks and flexible cycling options make it a must-have for millennial managers aiming to optimize mental performance.







| ASIN | B0896SS176 |
| Best Sellers Rank | #55,270 in Health & Household ( See Top 100 in Health & Household ) #2,278 in Blended Vitamin & Mineral Supplements |
| Customer Reviews | 4.2 4.2 out of 5 stars (158) |
| Date First Available | May 28, 2020 |
| Department | unisex-adult |
| Manufacturer | Nootropics Depot |
| Package Dimensions | 2.91 x 1.46 x 1.34 inches; 0.88 ounces |
C**S
Really amazing!
This stuff is great! I can only take a quarter or a third of a pill in the morning because it lasts for a good 12-15 hrs and if I take it too late I'll be up all night. I'm a software engineer and it feels like I have limitless concentration and capacity to work through problems all day. I break open a capsule and dump a third into some juice and it mixes in. With coffee it's a lot of energy! I can't really compare it to anything else I've taken but it's great. It's more a feeling of alertness and having your brain feel "on" or "activated" than that jittery feeling you get from coffee or other stimulants. I take it with Alpha Brain and eat eggs in the morning to get extra choline and acetylcholine. CDP-Choline would be another good option to stack with it so acetylcholine levels don't get depleted. This is pretty common with any nootropic. I'll probably cycle it like most other people do and take weekends off and maybe not take it every day. Other people have mentioned using polygala with it and I might try that too. Update March 23, 2024 - I've been using this since last October and it's still great. I still only use about half of a pill and still need to take it in the morning because it gives me a lot of energy (focus) for 12-14 hrs. I only use it a few times a week because taking it every day would be too much for me. I'm also taking lions main which has a similar action so the two are probably working together. It does feel like it's "regrowing my brain cells" which is a weird and great feeling. One side effect of neurogenesis like this is a little brain fog while the brain is restructuring these cells, so sometimes I take weeks off to let my brain go back to baseline. This is definitely worth trying, it's best with exercise and good amounts of sleep and eggs / choline. Nothing else quite like it. Update May 18, 2025 - Still using this a few days a week, only a quarter of a pill at a time but my brain is really sensitive to everything I take so maybe you can handle more. Still taking it with Alpha Brain, lion's mane, cordyceps, NAC, NMN, coffee, and eating eggs every morning. I still need to take it early in the morning so I can sleep at night. I still take weeks off. Exercise definitely feels great with this and helps balance the feeling of alertness. Also some Japanese sencha / matcha green tea is a great option (for the theanine) to help smooth out the effects if it's still going strong in the evening. Really glad I tried this stuff! It feels like I have the mental energy and capacity to keep creating and learning new things even later in the day when I would normally feel my energy drop a bit.
S**G
Wow
A serious brain booster. Take it early or you will be up very late.
M**X
Good neurogenic!
This is said to be a stronger version of normal 7.8-DHF and promote neurogenesis. While I don’t think it works as well as NSI-189, I can definitely feel it working. I’d say though that it’s pretty strong in general and it lasts a long time, so you should take it pretty early in the morning or else you might get some insomnia. I took it first at 2pm and I had some mild insomnia and the effects lasted even until I had the second dose!! I do say though I think the effects wear off over time or maybe the body just gets used to it, but over time the effects are less pronounced that when you first started. It could be due to it being a pure agonist of TrkB rather than a BDNF modulator. Either way, I’d recommend that it should be cycled for good measure. The price is okay and it has good value for money!
R**L
One of the few products with noticeable effects
I noticed enhanced memory recall and problem-solving, and an ability to make logical connections more rapidly. This is rare— I am usually disappointed but not this time.
W**M
Really good backup to have for going in public for me
I have really bad social anxiety, this helps give me the energy and motivation to push through hours in public when I don't want to do it. I only take a few times a month when I need them to help make sure they don't lose effectiveness. Good to have in the supplement toolbox, one of the more significant nootropics that actually does something.
D**Y
Creates dependency and causes withdrawal
Tried this product for a month was Really happy and even decided to buy another 30 count. Two days after waiting for my new bottle to come I caught an anxiety attack and started withdrawing from this product worse than a real drug . Definitely creates a dependency on it and a severe withdrawal with anxiety and a feeling that I wouldn’t wish on my worse enemy. More studies and research need to be performed before releasing it to the public because now I have to call out of work because it’s been 3 days and the anxiety has not gone away. My sister which is a doctor and is all for homeopathy also developed the same symptoms upon stoping usage.
J**W
Strongest supplement from ND
Easily the most impactful and noticeable nootropic from ND in terms of acute mood boosting, energy, and mental clarity effects. Only downside is that it can cause insomnia sometimes, but as long as you make sure to take it early in the morning, the insomnia effects go away. On another note, I just wanted to comment on another persons review claiming that it caused “dependency and withdrawal” - that’s just not true whatsoever. So many people who review things online are hypochondriacs. There’s nothing in this noot that has anything to do with dependency or withdrawal.
O**.
Uncertain about the efficacy and consistency of this compound
It worked particularly well for the first couple days I tried it, but has done nothing other than make it really difficult to sleep any time I’ve tried it since. It’s not necessarily promoting wakefulness at this point, but rather letting me feel the same level of exhaustion and also barely be able to stay awake instead of giving up and sleeping. There is no consensus on the safety of this product and could and probably is unsafe long term. I’d suggest trying it if you’re looking for something similar in use to phenibut or a low dose of modafinil, but it hasn’t worked for me in a while no matter how long I take a tolerance break for (up to a month)
A**F
How do I get the 90 count bottle in Canada it’s not worth buying the 30 count for $69 plus shipping and it takes a month to arrive. Please make the 90 count available in Canada!
A**R
No noticeable effect. Might be impactful if your body is lacking something but for a healthy individual this probably won’t do much.
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